Understanding distribution, epidemiology and the Social Determinants of Health related with HIV/AIDS are the basis on which we must work to achieve full containment of the epidemic in taking preventive measures such as clinical measures implemented for this purpose. Objective: To analyse intermediate and structural social determinants related to the HIV / AIDS reported in the national and international literature in the period 1993-2013. Material and methods: This research is hermeneutic, was developed in three phases: 1) Literature search and classification results. 2) Revision 3) Analysis of this literature with subsequent preparation of the final report. Results: met inclusion criteria 119 items. Eighty-four were for structural studies of determinants, 33 related to socioeconomic status, gender 25 and 26 with other structural determinants. Thirty-five were for intermediate DDS, 22 related to the conduct and 13 with the material conditions of life. Discussion: the structural determinants (gender and socioeconomic status) are those with a high probability of exercising greater constraint on the behaviour of HIV, and therefore require considerable efforts in this field to combat the pandemic.