The aim of the present study is to analyze the psychometric properties for the Spanish adaptation of the Connor-Davidson Resilience Scale (CD-RISC) ia sample of vulnerable teenagers of Colombia. Two psychometric studies were conducted: one for the 25-item version (CD-RISC-25) and other for the brief 10-item version (CD-RISC-10). All of the items showed good discrimination, with item-total correlations ranging from 0.29 (Item 14) to 0.75 (Item 25). Cronbach’s alpha was 0.88 CI [0.86, 0.90] for the 25-item version. Subsequently, an item screening was conducted in order to test a brief version. For the brief 10-item version (CD-RISC-10), a one-factor one-dimensional structure with very good fit was found through exploratory and confirmatory factor analysis. The exploratory factor analysis suggests that CD-RISC-10 could be considered a one-dimensional measure. Importantly, both CD-RISC-25 and CD-RISC-10 showed factorial invariance as a function of sex. In conclusion, the brief 10-item version of the Connor-Davidson CD-RISC presents appropriate psychometric properties to validly and reliably estimate resilience levels for vulnerable Colombian adolescents. Key words: resilience, vulnerability, CD-RISC, adolescence