Lepanthes caetanoae O. Perez E. Parra & Kolanowsla, a new species from the Colombian western range, eastern slope, is described and illustrated. This species is close to Lepanthes declivis Luer & R. Escobar, from which it differs by the non-reflesed apex of the lip and by the lanceolate shape of the leaves. In addition, information about its distribution and habitat is also presented.