The effect of “informatization” on all facets of our life is redefining the understanding of reality, human beings and their relations and (inter)actions. This paradigm shift requires new epistemic and ontological approaches, but also ethical and anthropological ones. Luciano Floridi’s information ethics and philosophy try to explain the effects of this turn towards information, in which engineering fields play a fundamental role. The “infosphere” is an ecosystem of information-based actions and relationships that blurrs differences between what is human and what is artificial. The capability for action of and interaction between machines and humans requires a reflection in which the understanding of information technologies is essential. Thus, the philosophy of information —as a philosophy of, for and in the modern world— must maintain a direct dialogue with the engineering fields.