This review article aims to describe the relationships established in the literature about patients with chronic pain cognitive factors and quality of life, for which a compilation of some of the investigative approaches was made in this regard. The articles published in recent years were taken from data bases limiting the results to clinical trials, meta-analysis, guidelines, and reviews, which were written in English or Spanish. As a result,different categories including beliefs, cognitive assessment, and self-efficacy expectations as intermediaries for coping strategies that determine quality of life were found. Among them,having self-efficacy higher expectations and internal locus of control have more adaptive consequences in subject’s life. It is necessary to have greater access to information and better methodological designs to compare the results between them.