The main purpose of this research was to stablish the level of maturity of research projects developed by INTERFAZ research group at the Industrial University of Santander, such a strategy oriented to build real capabilities to develop new technology-based products with innovative potential such as medical devices for orthopedics. This vision was carried off value creation supported by low cost for emergent economies health system such as Colombia, therefore these technologies allowed to improve the orthopedic and maxillofacial surgery practices. According to the capabilities approach, the University was defined such main stakeholder working together with its University Hospital, other research groups, and suppliers. The innovation capability was studied on 10 research projects, which were developed in collaboration with RD this vision was according to an organizational approach and was implemented in those practices for knowledge transfer and technological management. In this way, since building capabilities approach, this research has been a contribution to generation and development of different technologies with potential value creation and likewise the built capacities to made in the future short, medium and long-term projects.