In this article, notes are shared about the decoloniality of the social since the claims that, the diversities of Latin America and the Caribbean pose to the modern contemporary capitalist society. Through the review of documents, participation in social processes and reading of those who question social realities as a source of knowledge and action, it was possible to establish a route of questions, to identify the social in the claims of them, interpret in historical perspective and connect them with the disciplinary concerns of Social Work. The results indicate that the contexts and meanings of what is claimed, correspond to manifestations of an old colonial wound still in force with the colonial power over beings, their relationships and achievements but also propose other life options. Their contents are close to Social Work and increase their chances of conceptualizing rigorously the social, strengthening their critical positions. They propose a decolonizing turn of the anthropocentrism, towards the centrality of life as a source of transformation and social liberation.