This research establishes , through a case study , the internal and external policy guidelines that led to eradicate successfully cases of extreme poverty in Bucaramanga, Colombia, with the implementation of a national strategy named “Red Unidos”. To this end, thoroughly investigated the implementation of this strategy in the city since its creation, finding structural factors that allowed the advantage of Bucaramanga , comparing with other national cities, in the proportion of its population living in extreme poverty; internal guidelines on the behavior of Red Unidos operators in the municipality explain the differentiating substantial outcomes which promote families since 2008 ; and external aspects of regional and local public policy should be redesigned to achieve a complete eradication of extreme poverty in the city .