This report presents an initiative to structure and implement a line of pedagogical practice oriented by the strategy project-based Learning (ABPY), supported by the theory of meaningful learning and the gold standards for The design of projects, proposed by the Buck Institute for Education (BIE) in the program of Bachelor of Basic education with emphasis in natural sciences and environmental education, attached to the Faculty of Education of the University of Antioquia, in the city of Medellin, Colombia. The process of formulation and postulation of the proposal is presented, the Working group formed and the projects structured and applied in different educational institutions of the city.