This article is based on a descriptive study with a mixed approach and non-experimental design, whose objective was to evaluate the psychological reactions present in parents and / or pediatric oncological patient caregiver in the city of Bucaramanga during 2017; 40 participants were selected in a non-probabilistic manner, for convenience, and they were applied the inventory of state / trait anxiety STAI, inventory of depression state / trait IDER and scale of appreciation to stress EAE. It was found that 42.5% of the participants scored in high average anxiety levels for state and 42.5% for high trait anxiety, on the other hand the results related to depression show that 40% of the sample presented depression type state and 25% scored for trait type depression; In terms of the scale of appreciation to stress, there is a parallel between low level and high level with 45% for each parameter.