The negation of domination rule[1] is one of general and applicable rules of jurisprudence, such as Shi'a and Sunni, especially has an important role in Islamic international relations. Based on religious teachings, needs and necessities of life of present age should be related to other nations and governors in different aspects of politics, culture and economics. For these relationships, Islam outlines principles, including the of negation of domination. According to this principle, which is derived from verses and traditions of infallibles, maintenance of independence and dignity of Islamic State and Muslims and negation of any domination and influence in various dimensions is necessary. Of course, application of this is possible in foreign relations, and in some cases it is in conflict with principle of keeping a vow that it seems that although original is on primacy of of keeping a vow, in general, one of two principles cannot be applied to other before but in each case, it should be done according to interests of Islamic State and Muslims and rule of important and more important.