Objective: This study examines drug tendencies of medical science students.Study Design: Cross-sectional study.Place and Duration of study: 3 months in Kerman University of medical scienceMaterials and methods: This descriptive study was conducted on 413 (from 645) students, ages of 18-19 years old, of the colleges affiliated with Kerman University of Medical Sciences for 60 days from November 3, 2014, to January. 2, 2015. Data analysis was done by SPSS software version 21.Results: Medical students had gained highest average score (12.26 ± 2.68) and management students had gained the lowest average score (10.40 ± 2.31) in the environmental dimension tendency toward drug addiction. The highest average of the total drug tendency was for laboratory non-continuous students (and the lowest average of the total tendency was for midwifery students (34.23 ± 5.80). May it could be because of their female gender. There is also a significant difference between the total score and the different dimensions of drug tendency in terms of field of study. Conclusion: The main cause of drug orientation among students is social dimension especially friends. The emphasis of families and Higher education officials is on choosing a good friend. Student justification provided by the Department of Cultural and Student Affairs Can be helpful.