One of the dangers that has frequently threaten many cities and their construction projects throughout the world, including our country, is earthquake. Meanwhile, Iran is located in a seismic area in the world, which would indicate there is a threat to the country’s cities and residential buildings. With respect to the significance of the subject, the evaluation and quest of a method, which leads us to minimize seismic hazards, takes priority in the effort initiated by the article. In the article, an attempt was made to make a good estimate of the vulnerability of the city of Ali Shahr in Bushehr Province by using analytical graphical possibilities of geographical information system (GIS). Moreover, using GIS and descriptive data about the component and elements of buildings as well as various qualities of comprising elements, and mining field data from the scope of the study, we can make good prediction about the seismic behavior of the buildings against earthquake with available records. The results made it clear that there is a specific relationship between vulnerability indicators, the quality of foundation, roof, age of building, and type of building materials. As for all the available data, it has been evident that as foundation had 82% of poor quality, so did ceiling, building skeletons with 58% and 57% respectively.