The paper describes practical aspects of innovative development processes in the Republic of Tatarstan. The dynamics of innovative processes in the Republic of Tatarstan is presented on the basis of introduction of advanced production technologies. The indicators of innovative activity of enterprises for the last ten years are analyzed. Classification of innovative enterprises by types of economic activity was carried out.The strategy of innovative development of Tatarstan is reflected. The main focus is on the application of the cluster approach which involves interaction of science, education, business and authorities. The specifics of the innovative infrastructure functioning in the republic are revealed, the task of which is to create an effective mechanism for the transfer of technology, the commercialization of innovations, and the production of competitive products.It is determined that the maximum effect from the introduction of innovations depends on the innovation process structuring quality. The managerial recommendations for stimulating innovation at the regional level are reflected.