At the present stage of development of the Russian economy one of its main tasks is to transition to an innovative model of development (Akhmetshina & Mustafin, 2015). Payment systems play a vital role in the economics of each country. Payment systems have evolved through the history of the human race, starting out at the most primitive level of a simple exchange of goods, or barter, resulting in credit and debit cards, with their internet payments and mobile banking.This article is devoted to the role of International Payment System MasterCard and Mir in the work of economics of USA and Russia. The relevance of research is to analyze the process of integration of payment systems MasterCard and Mir in international trade and its impact on the development of countries. The authors studied and analyzed economic trends for the business year 2017:Analyzing the International Payment system MasterCard is important to note its rate of development. MasterCard took the first place by the number of card issued in the Russian Federation (on MasterCard accounted for 48, 9 % of all issued plastic payment instruments in the country) (Mastercard, 2016): (i) Despite the high status of MasterCard in the world of payment systems, he is trying to protect himself. There is a noticeable increase in the number of secure digital transactions (the amount of spending on contactless transactions on MasterCard cards increased by 183%, the availability of MDES, SecureCode, MoneySend, MasterPass work towards this) (Mastercard, 2016) and (ii) Pursuing the Russian Payment System Mir, it can be noted that it has become a domestic alternative to the international services of MasterCard and Visa, «protection against sanctions». Thus, it is essential to say that in spite of a young age of Mir payment system there are large prospects for existence of this payment system in Russia. Nevertheless, MasterCard keeps a leading position. Based on the indicators of this research it is obvious that the article has a high practical significance and the possibility of applying the results in both scientific and practical activities.