This reflective article tries to analyze the processes, dynamics and actions that constitute the political of the Indio Manuel Quintin Lame and their relation through the decolonial turn. It is part of the reflection of two central texts of this thinker: the first, defense of my race and the second thought of the Indian who was educated within the Colombian jungles said works represent a substantial part in the thinking of One of the most important leaders of the 20th century in Colombia. For this reason, we start by recognizing that the praxis from the set of ideas, actions and speeches of Quintin Lame was a fundamental piece in the territory, organizational and vindictive consolidation that is found within the communities in Tolima. The applied methodology consists of: extensive documentary analysis, review and theoretical reflection related to the decolonial perspective and its link with Latin American movements. As a result, Quintin Lame's political is an important component in the constitution of the Tolima movement, and has a great representation with the phenomenon of the indigenous struggle in Colombia.