Introduction. Skin lesions such as pressure ulcers and dermatitis associated to incontinence are a problem linked to age, mobility, moisture, food, elimination or mental state, which adversely affect the quality of life of individuals and their families. Their prevention through education can reduce their appearance and contribute to providing quality care. Objectives. To strengthen the knowledge in terms of prevention of skin lesions of nurses and caregivers of people hospitalized at a Bogota’s University Hospital in the internal medicine and intensive care units. Material and methods. A prospective intervention study, with an input diagnostic test to identify the knowledge of the nursing team, followed by three educational interventions. Then a test was applied to chart the changes achieved.