The purpose of this article is to present an analytical approach on the process of the extradition of Colombians as requested by international courts of justice, with reference to the author’s professional experience in the Foundation for the Defense of Colombians with Orders of Extradition (DECOPEX). This non-governmental organization was a space for the relatives of the persons arrested as a result of the extradition request from a state. The prisoners themselves were held in Pavilion Seven of the maximum security prison of Combita. The primary activities of DECOPEX were focused on four strategic areas: 1] the defense of the fundamental rights of the inmates and their families; 2] the development of a legal strategy at the national and international levels; 3] the lobbying of government bodies with the aim of regulating the legal procedure of extradition; and 4] making known to the members of society the problem that some people had been wrongfully arrested.