Aquaculture is seen as a good alternative for increasing the rates of animal protein consumption besides having the potential to promote social and economic development of a country. However, the fisheries may become a major source of disseminator pathogens responsible for several diseases for end consumers. During the aquaculture production cycle, in special frog breeding, a wide variety of microorganisms can be identified without necessarily causing disease in farmed animals; however, these can act as routes of transmission of pathogenic agents for end users, especially for humans. Gram negative bacteria, specifically those belonging to the Enterobacteriaceae family are involved in the majority of foodborne poisoning circulated in humans for fisheries. Another point to be considered is the resistance of pathogenic bacteria to antibiotics, which constitutes a serious problem in developing countries, due to failure or even lack of supervision and control over the use of antimicrobial drugs.