Since the advent of printing, publishing organizations have maintained, with some minor variations, a business model based on selling copies. Given the developments that have taken the needs of the customers of these organizations, derived from the avalanche of media brought about by the digital revolution, the business model of selling copies is insufficient. This research aims at presenting a business model based on knowledge management as an alternative to deal with the threats currently facing the publishing organizations. To propose a model of this type, initially a tour will be conducted by the history and evolution of the publishing organizations, then, the main features of the current publishing organizations will be described, and the opportunities that the digital revolution presents for publishing organizations will be identified. Finally, the proposal of a business model based on knowledge management to publishing organizations will be specified, with some general guidelines for implementation.