The article proposes the concept of creative mediation. It argues that the communication, as a sense sharing in which subjects share a mental object (thought, idea, feeling, meaning, etc.) can be planned from a mediation. This mediation will be creative to the extent that interacted innovatively (looking for new meanings, transforming or reconstructing) cultural frameworks, codes and technologies for building messages or different contents. Concludes that this form of mediation, thanks to the possibility of new technologies and the critical thinking of the subject, may be used in a cultural transformation.