This paper presents various historical social and cultural characteristics that occur in the work Sin remedio wrltten by Antonio Caballero, which reflect the permanent experiences in which has been involved mainly Colombian society since the sixties years. This paper seeks primarily a historical, social and cultural approach to modernity and modernism, in order to access the basis of what is known as post-modernism, this first step is done world, Latin American way and finally national in order to have an overview of different contexts. Later postmodern aspects found in the novel and reality ranging from the past (sixties and eighties years) to the present, which are visible from that makes up the multiple contexts of Colombian society characteristics are analyzed. Continuing the analysis of the work, elements such as loneliness of subjects, metafiction and self-awareness, poetic composition, roles of individuais in society, as well as time and space which form the main structure are studied work helping to (Ilustrate what can be considered as postmodernist In Colombian society.