El dengue es una infeccion viral sistemica transmitida a los humanos por la hembra del mosquito Aedes aegypti. Alrededor del 10% de los pacientes con dengue pueden presentar alteraciones neurologicas durante o despues de la infeccion. Existen unos signos conocidos como signos de alarma, los cuales, asociados al antecedente epidemiologico (procedencia de zona endemica), pueden ayudar a sospechar la infeccion. A continuacion, se presentan algunas generalidades sobre el virus, las formas clinicas, las complicaciones y el analisis de una revision sistematica de 65 historias clinicas de pacientes con diagnostico de dengue o dengue hemorragico. A partir de ellos, se encontro que se evidenciaron signos y sintomas neurologicos en 4 de los 39 casos que cumplieron los criterios de inclusion. Esta revision permitio detectar un caso de hemorragia en la cabeza del nucleo caudado, asociada a la trombocitopenia marcada, inducida por el virus del dengue. BASAL GANGLIA INVOLVEMENT IN DENGUE HEMORRHAGIC FEVER (DHF) ABSTRACT Dengue fever is a systemic viral infection transmitted to humans by the female Aedes aegypti mosquito. About 10% of patients with dengue fever may develop neurological disorders during or after infection. There are some signs known as warning signs, which, associated to the epidemiological background (origin of endemic area), may help to suspect the infection in those patients from endemic areas. Here are some generalities of the virus, its clinical forms, complications and the analysis of a systematic review of 65 clinical records of patients diagnosed with dengue and / or dengue hemorrhagic fever. From these patients, it was found that neurological signs and symptoms were evident in 4 of the 39 cases that fulfilled inclusion criteria. This review allowed to detect a case of hemorrhage in the head of the Caudate Nucleus associated with thrombocytopenia, induced by dengue virus.