Objective. This study seeks to discover the level of knowledge and access to information and communication technologies of individuals with chronic noncommunicable disease and family caregivers in Colombia. Methodology. This was a national, cross-sectional descriptive study with a sample of 2432 individuals with chronic noncommunicable disease and family caregivers located in different regions of Colombia, in whom we determined the level of knowledge and access to information and communication technologies. Results. In individuals with chronic noncommunicable disease and family caregivers low level of knowledge and insufficient access to information and communication technologies prevails. Conclusions. Information and communication technologies are significant tools in caring for individuals with chronic noncommunicable disease and in supporting family caregivers. Knowing their level of access and knowledge in the different regions of the country evidences a heterogeneous panorama that must be considered if the General System of Social Security in Health seeks to provide universal coverage.