The research is part of the issue of irregular migration in the light of the main provisions of public international law, namely, United Nations Convention against Transnational organized crime and the two protocols to the Convention: The Protocol to Prevent, Suppress and Punish Trafficking in persons, especially women and children, and the Protocol against the Smuggling of Migrants by Land, Sea and Air, all instruments adopted by the UN General Assembly in 2000. Although Colombia has ratified the Convention and Protocol on trafficking in persons in 2003, has done the same with respect to the Protocol on migrant smuggling, which is worrying cause the situation in Colombia as a country of origin and transit traffic people. The specific problem of this research is critically consider what are the institutional order obstacles that facing the country to comply with it is obligations to the international community in terms of prevention of both phenomena provided for these instruments as well as anticipate through recommendations what measures they should take to respond appropriately to these obligations. Achieving these both objectives is performed through a critical analysis not only of Colombian institutions and their effectiveness in terms of inter-state coordination to prevent the phenomenon, but also the scope of the international standards for states that, like Colombia, suffer its consequences, they can deal with the magnitude and characteristics with which it occurs in the present reality.