Objective: to determine the effects of gastric bypass on cardiovascular risk factors such as hypertension, dyslipidemia and diabetes in patients undergoing bariatric surgery in Colsubsidio Health Care Service Provider, Bogota, Colombia, and the proportion of patients with post-procedure success, defined as a 50% of excess weight loss in 1 year. Methods: Cross-sectional study. The sample size was calculated with a significance level of 5%, 80% power, assuming a proportion of patients with comorbidities of 40% and an expected rate after 1 year bariatric surgery of 10%, obtaining as at least 70 patients. There were 127 patients enrolled, among them, 106 (83,46%) were women; 114 patients (89,76%) underwent gastric bypass. Results: A significant reduction of comorbidities was found 1 year after gastric bypass in the proportion of patients with dyslipidemia, diabetes and hypertension, with a reducction of 60,25% (p<0, 001), 80,65% (p<0,001) and 78,05% (p=0, 01) respectively. Besides, an excess weight loss of 75,77% (p<0, 001) was founded, as well as a significant reduction of 2,8% (p =0,0016) in glycosylated hemoglobin levels. Conclusions: Bariatric surgery is a safe strategy for the management of diabetes mellitus in morbid obese patients with significant improvement in cardiovascular risk factors.