En la actualidad el sindrome metabolico se ha convertido en un problema de salud publica; la incidencia de este va en aumento y se constituye un aporte importante en los perfiles epidemiologicos de la region, el pais y el mundo, dado que causa enfermedad y muerte, siendo la enfermedad cardiovascular su principal consecuencia. Existen factores de riesgo que determinan la presencia del Sindrome Metabolico en los estilos de vida poco saludables, como son: mala alimentacion, sedentarismo y estres, los cuales generan patrones disfuncionales que deterioran la vida de un individuo. Esta investigacion pretende determinar la prevalencia de Sindrome Metabolico en los Comerciantes del Centro de Pereira, mediante un tipo de estudio descriptivo de prevalencia, con una poblacion de 218 comerciantes del centro de Pereira. Abstract Prevalencia of metabolic syndrome in the merchants of Pereira center, Au gust - November, 2008 Nowadays, The Metabolic Syndrome has become a public health problem. Its effect is increasing and It is now an important part of the region, country and world’s epidemiology that causes diseases and deaths; leading to cardiovascular disease as its main consequence. There are risk factors that determine The Metabolic Syndrome’s presence in people’s unhealthy life style’s habits, such as bad nourishment, lack of exercises, stress; which bring about malfunction patterns that deteriorates a person’s life. This research expects to establish that The Metabolic Syndrome prevails in Pereira’s downtown’s businessman. Prevail Descriptive study will be the type of health research done to 120 businessman from Pereira’s downtown’s population. Keywords: metabolic syndrome, risk factors, businessman, illness percentage.