The follow up of 92 cases of patients with cancer of the breast is presented. They were treated initially with surgery, and afterwards with a variety of adjuvant treatments. They were seen from July of 1983 to September of 1990. Of these cases, 35 belonged to premenopausal patients (Table No. 1) and 57 to postmenopausal patients (Table No. 2). Among the premenopausals, 15/35 (60%) had a positive axillary dissection while 14/35 (40%) had a negative one. Among the premenopausal females, 15/21 (71%) had a T1-2 tumor, and 6/21 (28.5%) had a locally advanced, T3 tumor. All the premenopausal patients with a positive axilla received postoperative chemotherapy. Of 21 patients, 10/21 (47.6%) recurred. Among the premenopausal females with negative axillary nodes, all 14 had a localized T1-2 tumor. Only 7 of those received adjuvant chemotherapy. Only one of the 5 patients who recurred had received chemotherapy. The 25-30 years old subgroup was particularly interesting. A total of 10 patients (10.8%) (Table No. 3) were seen. (Table No. 3). The results do not seem to indicate this is a subgroup with a specially adverse prognosis. Among the postmenopausal females (Table No. 2), 41/57 (71.9%) had positive axillary nodes while 16/57 (28%) had negative nodes. Of 41 postmenopausal females with positive axillary nodes, 36 (87.8%) had a T1-2 tumor and over 5/41 (12.2%) had a locally advanced tumor. Among the postmenopausal females with positive axillary nodes, 31/41 (75.6%) received chemotherapy. Of these, 18 out of 41 (44%) recurred. Of the 16 patients with negative axillary nodes, only one received chemotherapy.(ABSTRACT TRUNCATED AT 250 WORDS)