Oliver Sacks's work is well known and prominent in the medical literature for common people and has contributed to the understanding of neurological disease by the general public. Many authors from the point of view of literary neurology have analyzed his work. This article examines elements from the work of Oliver Sacks that could benefit the diagnosis approach and treatment of neurological patients and be a valuable contribution to the clinical practice of neurology from the perspective of a clinical neurologist. Some new contributions made by research in neuroscience and cognitive psychology to the holistic approach to the patient in medicine is also analyzed and the benefits of this approach in the recovery from neurological disease.