Secretions from the medium ear of 60 children with acute otitis media were cultured. In 66% of the patients we isolated bacteria: 29.9% H. Influenzue and 24.9% S. preumonial, as the Gram-predominant-germ. Studies were made on sensitivity and drug therapy. Sulfa-benzetacil was found the best combination, although amoxicillin continues to be the oral treatment of choice.