Among the wide variety of topics that relate to environmental issues and health, and in recent years has increased in the country control and the requirement that the environmental authorities are exerting on the health sector, integrated management is management of hazardous waste generated in these entities. This integrated management is the term applied to all activities associated with the handling and control of hazardous waste generated in institutions that provide health services which should ensure manage waste so that there is no risk to public health and no contamination in the environment. The above reason is just an incentive for the development of this degree work aiming at the development of the Management Plan of Hazardous Waste Oficentro ll Medical Center, based on the framework of national regulations and also proposing a series of strategies supported programs and instructions that eventually will serve as a guide or manual to implement and provide adequate and safe hazardous waste management in this entity. The Plan of Hazardous Waste Management involves aspects of planning, design, operation and management that defines the guidelines for integrated waste management strategies that provide reduce and properly dispose of hazardous waste and a series of indicators for effective verification and follow the plan.