Introduccion: Estres es el conjunto de procesos y respuestas ante situaciones que requieren mayor adaptacion que lo habitual. En estres psicologico, el individuo cree no controlar las exigencias del entorno. El objetivo fue estimar correlacion entre sintomas menopausicos y estres psicologico percibido. Metodologia: Estudio transversal del proyecto CAVIMEC (Calidad de Vida en la Menopausia y Etnias Colombianas), realizado en mujeres de dos ciudades del caribe Colombiano, edad 40-59 anos, que participaron voluntariamente en sus comunidades. Se aplico formulario de caracteristicas sociodemograficas y las escalas: Perceived Stress Scale (PSS-10) y Menopause Rating Scale (MRS). A mayor puntuacion de PSS-10, mayor estres psicologico. A mayor valor MRS, mayor severidad de sintomas, deterioro de dominios y peor calidad de vida. El analisis estadistico se realizo con Epi–info 7. Resultados: 471 mujeres con 48,0(45,0-52,5) anos. Premenopausia: 23,9%, perimenopausia: 11,7% y posmenopausia: 64,3%. El 61,9% en sobrepeso u obesidad, 7,2% diabeticas, 15,2% hipertensas, 15,7% ooforectomia bilateral y 50,3% histerectomizadas. 69,4% manifesto que las cosas le iban bien a menudo y 57,5 % que estaban seguras sobre su capacidad para manejar problemas personales. MRS 13,0(9,0-17,0) puntos, cansancio fisico/mental 84,5%, oleadas de calor 84,5% y dolores musculo/articulares 84,3%. Se encontro correlacion positiva entre oleadas de calor, molestias cardiacas, trastornos del sueno, molestias musculo/articulares, estado de animo depresivo, irritabilidad, ansiedad, cansancio fisico/mental, problemas sexuales, problemas de vejiga, sequedad vaginal y calidad de vida, con PSS-10 (p<0,005). Calidad de vida: rho=0,41(IC95%:0,33-0,48)p<0,0001. Urogenital: rho=0,39(IC95%:0,31-0,46)p<0,0001. Somatico: rho=0,31(IC95%:0,23-0,39)p<0,0001. Psicologico: rho=0,38(IC95%:0,31-046)p<0,0001. Conclusion: a mayor presencia de sintomas menopausicos, mayor estres psicologico percibido. CORRELATION BETWEEN MENOPAUSAL SYMPTOMS AND STRESS PERCEPTION IN WOMEN FROM THE COLOMBIAN CARIBBEAN ABSTRACT Introduction: stress is a set of processes and answers in the face of different situations that require greater adaptation than the usual one. In the psychological stress, the individual believes not to have control of the environmental demand. The aim was to estimate correlation between menopausal symptoms and perceived psychological stress. Methods: cross-sectional study of the CAVIMEC (Calidad de Vida en la Menopausia y Etnias Colombianas) project, carried out in women from two Caribbean cities in Colombia, between 40-59 years old who voluntarily participated in their communities. A questionnaire of sociodemographic characteristics and the scales: Perceived Stress Scale (PSS-10) and Menopause Rating Scale (MRS) were applied. A higher MRS score, higher severity of the symptomatology, deterioration of the domains and higher psychological stress. The statistical analysis was done with Epi-Info 7. Results: 471 women with 48,0 (45,0-52,5) years were included. 23,9% women were in premenopause, 11,7% in perimenopause and 64,3% in postmenopause. 61,9% were in overweight or obesity, 7,2% had diabetes, 15,2% presented hypertension, 15,7% bilateral oophorectomy and 50,3% were hysterectomyzed. 69,4% reported that things often were in a good way and 57,5 % indicated that they were sure about their ability to manage personal problems. The MRS score was 13,0(9,0-17,0), 84,5% indicated physical and mental exhaustion, 84,5% hot flushes and joint and muscular discomfort 84,3%. A positive correlation between hot flushes, heart discomfort, sleep problems, joint and muscular discomfort, depressive mood, irritability, anxiety, physical and mental exhaustion, sexual problems, bladder problems, dryness of vaginal and quality of life, with PSS-10 (p<0,005). Quality of life: rho=0,41(CI95%:0,33-0,48) p<0,0001. Urogenital domain: rho=0,39(CI95%:0,31-0,46) p<0,0001. Somatic domain: rho=0,31(CI95%:0,23-0,39) p<0,0001. Psychological domain: rho=0,38(IC95%:0,31-046) p<0,0001. Conclusion: To higher presence of menopausal symptoms, higher perceived psychological stress