Objective: The purpose of this study was to determine the statistical association between the diagnosis of alcoholic liver disease and alcohol sales by department based on the Individual Records of the Health Care Services (Registros Individuales de Prestaciones de Servicios de Salud RIPS) for 2012. Methods: This was a cross-sectional ecologic study conducted to compare prevalence rates of alcoholic liver disease estimated by RIPS (ICD K700-9) in the over 18 population (DANE) with sales, according to the National Federation of Departments, of domestic and imported spirits, liquors and beers, converted into alcohol units. Results: The national rate of alcoholic liver disease was 10.7 per 100,000 with higher rates in Santander (27.1), Risaralda (19.9) and Boyaca (15.0). After removing the data from departments with unreliable or incomplete results, the Pearson correlation rate of illness and alcohol unit sales was 0.6. Conclusions: There is a positive correlation between the rate of alcoholic liver disease and alcohol sales in each department.