Tooth movement during orthodontic treatment may generate an inflammatory or degenerative response in the pulp tissue. pulp tissue. When this tissue is exposed to mechanical loading with different magnitude, frequency, and duration, it expresses macroscopic and microscopic changes by inducing circular and vascular alterations. macroscopic and microscopic changes by induction of circular and vascular alterations. However, in most cases the pulp tissue tends to However, in most cases the pulp tissue tends to recover while maintaining its structure and function. Therefore, it has been suggested that the injury to the pulp caused by the It has therefore been suggested that the injury to the pulp caused by orthodontic forces is permanent, and that the pulp reticulum may eventually lose its vitality, despite a few studies denying this correlation. This inconsistency in the literature is probably the result of invalid interpretations. invalid interpretations. Accordingly, the aim of this literature review carried out at the Universidad Cooperativa de Colombia in 2010 was to Cooperative University of Colombia in 2010 was to understand how pulp pathology can occur in response to orthodontically induced tooth movements orthodontically induced orthodontic tooth movements and whether such effects are transient or permanent.