This work intends that spirituality is a political matter through theoretical articulation of work from Foucault and Lacan. For these two thinkers it is an exercise of transformation of the subject when it is in connection with the truth; and this act is political, since not only it allows the fellow's transformation but of all the coordinates that sustain the place where that fellow is located, that is to say: it transforms that subject's same reality and their relationships with the other ones. This transformation cannot happen from some logics traced ahead of time but from the incalculable thing, from an event. And this work is about outlining this act theoretically in relation to the subject and the truth, and how the psychoanalysis can sustain this event from its practices, and more in a time where the soul, the spirituality has been denied in many psychological practices, even in the psychoanalytical same practices, it is for that reason that from the road traced by Foucault from its proposal of practices of self, and the lacanian proposal of the analytic act we want recapture this spiritual road again, a mainly political road, a way for transforming the subject.