Introduccion: es importante sensibilizar a medicos generales y pediatras, sobre la necesidad de considerar posibilidad de pancreatitis aguda en ninos que presentan dolor abdominal. Caso clinico: paciente de dos anos de edad, con cuadro clinico de un dia de evolucion caracterizado por dolor abdominal, vomitos y fiebre no cuantificada. Con antecedente de hospitalizacion al nacer, por sepsis neonatal y enterocolitis necrotizante, manejada con nutricion parenteral y dialisis peritoneal por haber presentado falla renal aguda. Al examen fisico de ingreso se encontro algida, estable, sin dificultad respiratoria, dolor a palpacion profunda en epigastrio e hipocondrio derecho y sin irritacion peritoneal. Hemograma, ionograma y pruebas renales fueron normales. Se encontraron cifras elevadas de amilasa serica. Se realizo diagnostico de pancreatitis aguda e instauro manejo hidroelectrolitico. Ecografia abdominal y TAC abdominal demostraron presencia de calculo en el cuello de la vesicular biliar, sin dilatacion de las vias y aumento discreto del pancreas. La paciente evoluciono de forma favorable con las medidas medicas y no presento complicaciones. Conclusion : la pancreatitis aguda en ninos es una patologia que ha aumentado de frecuencia en los ultimos anos. La presencia de dos de los tres criterios definidos, permite establecer el diagnostico. Rev.cienc.biomed. 2014;5(2):341-344. PALABRAS CLAVE Colelitiasis; Pancreatitis; Dolor abdominal; Nino; Pediatria. SUMMARY Introduction: it is important to make the physicians and pediatricians aware of the necessity of considering the possibility of acute pancreatitis in children who present abdominal pain. Case report: a two-year-old patient with symptoms of one day of evolution characterized by abdominal pain, vomiting and unquantified fever, with history of birth hospitalization because of neonatal sepsis and necrotizing enterocolitis treated with enteral nutrition and peritoneal dialysis due to have presented acute renal failure. At physical examination she was found stable, with pain, without dyspnea, with pain to the deep palpation in epigastrium and right hypochondrium without peritoneal irritation. The hemogram, ionogram and the renal proofs were normal. Elevated values of serum amylase were found. The diagnosis of acute pancreatitis was done and hydroelectrolytic management was initiated. The abdominal ultrasound and the abdominal computer tomography (CT) scan reported presence of calculi in the neck of the gallbladder without dilation of the tracts and discreet increase of the pancreas. The patient progressed in a favorable way with the medical management and she did not present complications. Conclusion: acute pancreatitis in children is a disease that has increased in frequency in the last years. The presence of two of three defined criteria allows to establish the diagnosis. Rev.cienc.biomed. 2014;5(2):341-344. KEYWORDS Cholelithiasis; Pancreatitis; Abdominal pain; Child; Pediatrics.