Bioinformatics is the use of computational tools for analyze, debug and streamline the handling of large amounts of data in biology in terms physicochemical and help to understand and organize the information associated with it. Bioinformatics starts from data found experimentally, which are stored and apply later techniques for consultation, analysis and knowledge extraction. One of the central issues in this field today is to define the storage schema and tools for analyzing large volumes of data generated and available. 1 Ingeniera Industrial, Ingeniera de Sistemas, MSc. En Administracion. , Doctorando en Ingenieria Informatica 2 Ingeniera Electrico, MSc. en Administracion. Doctorando en Ingenieria Informatica This article presents a review of bioinformatics research needs and approaches to data storage and processing, which shows that a concern of researchers is related to the ability to leverage the data and to extract information and underlying knowledge. The analysis leads to the conclusion that take advantage of the technologies associated with data warehouse is presented as a promising solution, but requires decisions that will shape the final outcome. Key Word — Bioinformatics, data warehouse, OLAP, dataminig.