To obtain a coffee variety resistant to canker disease caused by Ceratocystis fimbriata (Cf), a line of Coffeea arabica var. Borbon resistant to macana-canker (Brm) was crossed with susceptible Caturra variety. The aim of this study was to evaluate progenies F5 to select highly resistant progeny with good agronomic and quality attributes of grain. A virulent isolation CF117P Cf was inoculated into the stems of nine-month-plants grown in plastic bags of 13 progenies, Caturra and Brm as controls, in fully randomized, one plant as the experimental unit and 30 replicates. A year later the survival plants, length and width of necrotic area (cm) on the stem of these plants were measured. In adult plants in field 15 progenies were evaluated in two assays, in fully randomized, 10 plants per experimental unit and 5 replicates per each progeny, including the same test controls. The plants were inoculated at 15 months old in the first assay and 20 months in the second assay. In the first one, the evaluation was made 13 months later by recording survival, length and width of the lesion. Forty-eight months after inoculation the survival of plants in both experiments were assessed. In seedlings, all progenies and Brm survived between 81% to 93%, and 96% in Brm. In field experiments, the resistance response coincided in 90% with seedlings results. Eight highly resistant progenies, performing high yield and cup quality, were selected with ≥80% survival, shorter length and width lesions at the inoculation site. Ninety- nine porcent of the Caturra plants died.