This paper aims to show the transition from Boyaca Sovereign State to Political and Administrative Department during the Regeneration period from 1886 to 1903. This process was accompanied by a set of economic, political and social reforms. These reforms consolidated a new national unity project based on the Constitution of 1886. The Regeneration was presented as a political project that changed the relations between State and society. This project also affected regional autonomy as a result of a dependency on central government. Regeneration is a stage where going from a federal system to a centralist one becomes evident, in order to build a model of citizen that responds to the dreamed construction of a unitary nation. The author bases her work on journalistic sources such as the Diario Oficial, El Boyacense, El Espectador, among others, and on a large bibliography on Federalism and Regeneration.