Tests applying quasi-static and/or dynamic loads are an essential tool to study the performance of materials and structures. Results of these tests allow to analyze the behavior of the specimen according to the type and magnitude of the stress that it will be submitted. Pneumatic actuators are a suitable option to simulate quasi-static loading on small specimens because the cost is low when compared with other actuators. This article shows the results of the automation of pneumatic actuators that are attached to mini-load frames. The characteristics and response of the mini-load frame system are initially described and discussed. It is then explained the design of the control systems such as a classic PID and self-tunnig regulator. In addition, it is described the displaying and data acquisition system. Finally, results of tests performed in a real environment are shown and discussed, operating the system fully automated and the force and displacement control implemented. The proposed automation for pneumatics actuators is practical, economical, and increases competitiveness, relevance and validity of the results obtained in the tests of materials and small structures.