Graphic designers, who also work as professional communicators, are immersed in the speed and technology of the globalized world. His practice has changed in many ways, reaching today to new environments such as cultural and creative industry. One of these environments is the museum, which has evolved in many ways also, to be classified today as part of the dynamics of the cultural industry and itself as a favorable place for the performance of the graphic designer. Jesus Martin Barbero talks about the work of social communicators, suggests today they go from being intermediaries to be mediators and participants in the construction of another society. This leads us to understand the graphic designer as communicator-mediator who professionally should use strategies, knowledge, skills and competencies to play a leading role in the cultural industry. This industry is a phenomenon that hosts the transformations of contemporary society, on issues such as culture, globalization and information, it is the repository of discussions on the modes of production, marketing, reproduction and conservation of goods and symbolic services. This work establishes that the convergences and metamorphosis that are defining the museum today overlap with the changes in the performance of the graphic designer as a professional communicator. Also reveals interrelationships and new configurations studied from the perspective of communication, it understood as a system for the reproduction of symbolic capital and mediator in the context of the cultural industry.