Today innovation plays a distinctive role in organizational competitive strategy, so that these processes management becomes key factor for success and above all the sustainability of processes inherent to the activities of research, development and innovation (RDi).This quantitative and correlational scope project aims to determine the relationship of aspects which handles the technical standard NTC 5801 Colombian innovation management with those in small and medium-sized enterprises (SMEs) textiles and clothing in the city of Manizales. The methodological instruments, validated by a panel of innovation experts in the region and external expert consultant in standard and treated statistically using SPSS program, were applied to the