in this paper, the geometry and dimensions of a human femur was generated through 3D scanning process, to obtain the femur external topology. The internal structure was obtained through morphological studies based on radiography and tomography, in order to determine the right proportions and dimensions of the internal femur. Then, the complex structure of the femur was represented through three dimensional finite element model, built with Comsol. This model was simulated with isotropic and anisotropic materials, subjected to various mechanical loads according with experimental reference studies. The reference studies, was developed using dual energy X ray absorptiometry (DXA), quantitative computed tomography (QCT) and real human bones, which was subjected to specific loads in order to establish an objective basis for comparison. The main goal of this study is to determine the femur mechanical strength using finite element technique, validating the results by comparison with experimental studies.