Global warming will lead to changes in rainfall patterns over the planet. As a consequence, it will modify streamflow behaviour too. The change of runoff regime implies not only changes in mean values, but also changes in extreme values. These extreme values represent drought runoff and high peak runoff from floods. Floods are an important factor for structural design of bridges for roads/river intersections. Usually, bridges are designed for stationary hydrologic conditions, implying that the probabilities of maximum flows are constant in time. Due to the climate change process, maximum flow values that are used as critical values for structural bridge design could be underestimated for regions where an increase of precipitation is expected. Therefore, a climate change sensitivity analysis of maximum flows is necessary. This sensitivity analysis will allow an assessment of the vulnerability of hydro­structures designed under assumption of stationary hydrological conditions. This paper presents an approach for sensitivity assessment of maximum flows under climate change conditions. This methodology is applied to three bridges with different levels of hydrometeorological information availability. For the chosen case studies information availability varies from good to poor. Finally, conclusions about the pertinence of using climate change as a key factor for design of major hydrotechnical structures are made.