This paper presents the results of an applied approach to the automation of a micro-filtration plant used for the treatment of tropical fruit juices. Based on the assessment of the operation conditions of the original plant, through the analysis of the variables and control loops, the instruments selected for the automation and control of the operation variables and the computational tool used for the acquisition and data registry are described. In addition, the plant subsystems control loops adjustment methodology, which is based on reaction curves and heuristic techniques, is shown.