Introduction and objective: There is evidence about the relation of periodontitis and some conditions and systemic illnesses. The biofilm bacteria and its inflammatory response promote a local and systemic response. The scope of this pilot study was to explore the knowledge and attitudes of a sample of specialist physicians of Medellin, regarding the relation of periodontitis, premature and low weight birth, and cardiovascular diseases, as arteriosclerosis and myocardial arrest and stroke. Materials and Methods: A descriptive pilot study was performed, where surveys were carried out on specialized physicians working by Service Companies (EPS) or in their own consulting offices in Medellin, Colombia, who accepted to reply the survey. A pilot test was first performed to ensure the comprehension of the survey questions. Results: Of the asked physicians, 69,9% said know about the periodontal disease, 21,7% have read something about, but do not know it deeply, and 8% do not know anything about. However, only 40,8% of the surveyed specialized physicians take it into account, when enquiring on the clinic history of their patients. Conclusion: The relation of periodontitis and systemic events is still regarded with care by the medical communities and they are not convinced of its biological rationalization yet. Key words: Periodontitis, Diabetes mellitus,