A new meroterpene derivated of the 2-quinolone, 7-O-neril eter de 2-quinolona (1) and three derivates of labdane, have been isolated from the fresh leaves of Zanthoxylum rhoifolium LAM (Rutaceae), two epimers (13S)-labdane- 8α,15-diol (2) and (13R)-labdane-8α,15-diol (3) and a third one 13(S)-8α-13-epoxilabd-14-ene (4). These compounds had not been reported before for genus Zanthoxylum. Their structures were established by 2D-NMR spectroscopic techniques (IR, NMR one-two dimensional and ME).