To carry out this project a descriptive correlational design was used in order to identify the existent relationship between coping strategies, self-esteem, anxiety levels and depression in a group of 17 adult patients diagnosed with cancer. The Rosenberg Self-Esteem Scale, The Hospital Anxiety and Depression Scale (had) and the modified Coping Strategies Scale (eec-m) were applied for this purpose. This research showed the following results: A correlation between anxiety and self-esteem levels, anxiety levels and coping strategies for problem solving, positive reappraisal and aggressive reaction. Likewise, a meaningful correlation between depression levels and coping strategies for problem solving, negation, aggressive reaction and the expression of the coping difficulty were observed.