The aim of this study was to evaluate the level of depression in patients hospitalized with different illnesses. A sample was taken of 82 patients of ages ranging from 22 to 76, to whom the Beck Depression Inventory (BDI-II) and the Hospital and Anxiety Depression Scale (HADS) were applied. The data were processed with SPSS 11.5, which produced the following results: 1) A prevalence of 41.5% depression in the sample according to BDI-II. 2) A prevalence of depressive dysfunction of 11% in the sample, according to the HADS. 3) higher prevalence of somatic-motivational symptoms compared with cognitive-affective symptoms. These findings correspond to those mentioned in publications, highlighting the high prevalence of depression in hospitals; equally, they confirm the importance of the evaluation of cognitive-affective symptoms to determine the presence or otherwise of depression in this type of patient.