2 , considerando significativo a todo valor de p<0,05. Resultados: 269 ninos tenian peso normal (84,5%), 29 presentaron sobrepeso (9,11%) y 20 eran obesos (6,28%). No se encontro asociacion significativa entre la sensibilidad insulinica y el estado nutricional. Hubo diferencia significativa en las glicemias en ayunas entre escolares y adolescentes eutroficos y con sobrepeso (p< 0.001). Conclusion: No hubo insulino resistencia en escolares ni adolescentes. El indice HOMA alcanzo un valor cercano a 1, y el indice de QUICKI se mantuvo alrededor de 0,40 independientemente del estado nutricional. Palabras clave: Insulina- HOMA- QUICKI- Escolares- Adolescentes SUMMARY: Introduction: Insulin resistance contributes to the physiopathology of diabetes and is the previous step to obesity, metabolic syndrome and many cardiovascular diseases; therefore the importance of its early detection. Objective: to evaluate the degree of insulin sensitivity by means of the indexes HOMA and QUICKI and the association with some biological variables (age, gender, nutritional state). Methods: the study is descriptive, of transverse cut type an d included children and adolescents between 6 and 18 years. Body Mass Index was calculated and the categorization was performed by Fundacredesa's charts. Glucose and insulin were measured in blood. Basal insulin sensitivity was calculated by means of the indexes HOMA, (blood fasting sugar (mmol/l) x fasting insulin (mU/l)) / 22, 5 and QUICKI (1 / (Log fasting blood sugar (mg/dl) + Log fasting blood insulin (µU/ml). Descriptive statistics were calculated and differences were studied by means of the test X 2 , considering as significant, values under 0,05. Results: there were 269 children with normal weight (84,5 %), 29 were overweight (9, 11 %) and 20 were obese (6, 28%). There was no significant association between insulin sensitivity and nutritional state. There were significant differences in fasting blood sugar between normal and overweight children and adolescents (p<0,001) Conclusion: there were neither children nor adolescents with insulin resistance The HOMA index reached a value of 1 and the QUICKI index was near 0,40 independently of the nutritional state.